![]() These yielded whole-head coverage at a 1-mm isotropic voxel size. Sagittal thin-section fast FLAIR is superior to conventional axial proton-density- and T2-weighted SE pulse sequences for detection of MS plaques in the brain. The ZTE sequence had the following parameters: 3D imaging mode with sagittal acquisition TE 0.016 ms, FOV 18 × 18 cm, readout matrix 180 × 180 × 180, section thickness 1 mm, NEX 1, receiver bandwidth 31.25 kHz, flip angle 2. MR of the brain using fluid-attenuated inversion recovery (FLAIR) pulse sequences. A subependymal striated appearance observed in several cases is believed to represent early inflammation and/or demyelination around subependymal veins in MS. In 43% of patients considered to have normal SE images, fast FLAIR images showed abnormalities consistent with MS. /rebates/&252fajnr-silenz-pulse-seqquence. To compare thin-section, sagittal, fast fluid-attenuated inversion-recovery (FLAIR) magnetic resonance (MR) imaging with conventional axial spin-echo (SE) imaging for early detection of multiple sclerosis (MS) in the brain.Ĭonventional 5-mm axial proton-density- and T2-weighted SE images and sagittal 2-mm fast FLAIR images of the brain in five healthy volunteers and 25 patients with clinically suspected MS were evaluated and graded as normal or as showing possible or probable MS in a double-blind study.įast FLAIR was judged better than SE in 37% of cases, equal to SE in 63%, and never worse than SE. The purpose of this study was to compare Silent T1-weighted and unenhanced MR angiography (MRA) against conventional sequences in a clinical population.
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